| Khoom npe | Phenyl pentanoate |
| CAS Nr | 20115-23-5 |
Chemical Properties
Cov tshuaj no feem ntau ntsib raws li cov kua pob tshab tsis muaj xim nrog cov txiv hmab txiv ntoo tshwj xeeb, kua txiv -zoo li tsw. Qhov kub kub yog kwv yees li 245℃ntawm atmospheric siab, thaum lub melting point nyob rau hauv qab no -20 degree, paub meej tias nws cov kua hauv lub ambient tej yam kev mob. Kev ntsuas qhov ceev yog kwv yees li 1.02 g / cm³ ntawm 20 degree, nrog cov qauv molecular ntawm C11H14O2 thiab molecular hnyav ntawm 178.23. Nws yog dawb do miscible nrog cov organic solvents xws li ethanol, diethyl ether, acetone, thiab toluene, thaum pom cov solubility tsawg heev hauv dej thiab negligible affinity rau aqueous alkaline daws. Cov ester txuas yog raug rau hydrolysis nyob rau hauv lub zog acidic los yog yooj yim tej yam kev mob, yielding phenol thiab pentanoic acid. Kev khaws cia rau hauv cov thawv kaw nruj nreem tiv thaiv los ntawm lub teeb thiab qhov hluav taws xob hauv qhov chaw txias, qhov cua zoo yog pom zoo vim nws qhov xwm txheej. Kev sib cuag nrog cov muaj zog oxidizing cov neeg ua haujlwm thiab cov hauv paus muaj zog yuav tsum zam kom tsis txhob decomposition.
Kev piav qhia
Phenyl pentanoate sawv cev rau qhov yooj yim tshaj plaws ester tsim los ntawm phenol thiab pentanoic acid, combining ib qho aromatic moiety nrog ib tug ncaj - saw aliphatic acyl pawg. Cov molecule nta ib lub nplhaib phenyl txuas nrog los ntawm kev sib txuas ntawm ester mus rau ib qho yooj yim tsib-carbon saw, tsim kom muaj cov qauv sib xyaw nrog cov ntu nruj thiab hloov tau yooj yim. Cov pab pawg carbonyl uas nyob ib sab ntawm phenolic oxygen qhia ib feem ntawm ob daim ntawv cog lus uas txwv kev sib hloov thiab cuam tshuam rau tag nrho cov molecular conformation. Qhov no unadorned architecture ua rau lub compound ua qauv zoo tagnrho rau kev kawm esterase kev ua ub no, vim tias tsis muaj cov pab pawg ua haujlwm ntxiv tshem tawm kev sib cuam tshuam. Cov ester daim ntawv cog lus yog nruab nrab polarized, ua rau nws raug rau nucleophilic nres los ntawm dej los yog enzymes thaum tseem txaus ruaj khov rau tuav nyob rau hauv ib txwm tej yam kev mob. Nws cov qauv ncaj nraim belies nws cov nqi hluav taws xob raws li kev soj ntsuam rau kev nkag siab cov ntsiab lus tseem ceeb ntawm ester hydrolysis hauv cov kab mob lom.
Siv
Enzyme Kev Ntsuam Xyuas
Hauv kev tshawb fawb biochemical, phenyl pentanoate ua haujlwm tsis yog -natural chromogenic substrate rau quantifying carboxylesterase thiab lipase cov dej num. Enzymatic cleavage ntawm ester daim ntawv cog lus tso tawm phenol, uas tuaj yeem kuaj pom colorimetrically los ntawm kev sib txuas nrog chromogenic reagents lossis ncaj qha los ntawm kev nqus ultraviolet. Qhov no muab ib qho yooj yim, nruam spectrophotometric txoj kev rau kev txiav txim siab enzyme kinetics, inhibition tas li, thiab substrate tshwj xeeb yam tsis tas yuav tsum tau rau derivatization los yog sib cais cov kauj ruam.
Kev kuaj mob Neurotoxicity
Lub compound yog ua hauj lwm raws li ib tug diagnostic cuab tam rau kev ntsuam xyuas neuropathy lub hom phiaj esterase inhibition nyob rau hauv cov kev tshawb fawb neurotoxicity. Organophosphate-induced qeeb neuropathy correlates nrog inactivation ntawm no enzyme, thiab ntsuas ntawm residual hydrolytic kev ua ub no rau phenyl pentanoate nyob rau hauv neural ntaub so ntswg homogenates muab ib tug ntau npaum li cas endpoint rau ntsuam xyuas lub peev xwm neurotoxic. Qhov kev ntsuam xyuas no tau raug tsim los rau kev tswj hwm tshuaj toxicology tshuaj xyuas cov tshuaj tua kab thiab cov tshuaj siv tshuaj.
Flavour thiab Fragrance Reference
Vim nws cov yam ntxwv ntawm fruity aroma profile, phenyl pentanoate yog siv raws li ib tug analytical standard nyob rau hauv lub zoo tswj chaw soj nstuam xyuas qhov tseeb thiab concentration ntawm tsw formulations. Nws muaj nyob rau hauv ntuj txiv hmab txiv ntoo essences thiab khoom qab zib muaj pes tsawg leeg yog saib xyuas los ntawm cov roj chromatography, nrog cov ntshiab compound pab raws li tus qauv calibration rau ntau yam tsom xam. Cov khoom no tshwm sim nyob rau hauv cov npe kev cai ntawm cov tshuaj tsw qab tso cai rau cov khoom noj thiab cov neeg siv khoom.
Qauv Substrate hauv Mechanistic Studies
Organic chemists siv cov ester no ua tus qauv substrate rau kev soj ntsuam cov tshuaj tiv thaiv cov txheej txheem ntawm acyl hloov cov txheej txheem, suav nrog transesterification, aminolysis, thiab hlau-catalyzed hydrolysis. Nws cov qauv yooj yim pab txhawb cov ncauj lus kom ntxaws kinetic thiab suav cov kev tshawb fawb txog cov teebmeem hnyav, hloov pauv, thiab txoj hauv kev catalytic. Cov kev tshawb fawb tseem ceeb no qhia txog kev txhim kho cov txheej txheem hluavtaws tshiab thiab muab kev nkag siab txog cov txheej txheem enzyme los ntawm cov qauv me me ntawm -molecule qauv.
Cim npe nrov: Tuam Tshoj phenyl pentanoate manufacturers, lwm tus neeg











