4-Amino-2-methylbutan-1-ol

Cov tshuaj no feem ntau ntsib raws li qhov tseeb, tsis muaj xim rau daj ntseg daj kua nplaum ntawm qhov kub thiab txias, muaj cov faint amine - zoo li tsw. Nws cov mis molecular yog C5H13NO, sib xws rau qhov hnyav molecular ntawm 103.16. Cov ntsiab lus kub yog kwv yees li 200-205℃ntawm atmospheric siab, nrog rau kev xam qhov ceev ze 0.96 g / cm³ ntawm 20 degree. Nws yog miscible nrog dej thiab cov kuab tshuaj organic xws li methanol, ethanol, thiab dichloromethane, qhia txog nws tus cwj pwm amphiphilic. Cov molecule muaj ob qho tib si thawj amine thiab thawj cawv sib cais los ntawm peb cov saw hlau nrog methyl ceg ntawm 2 txoj hauj lwm. Cov amine yog raug rau acylation, alkylation, thiab condensation tshwm sim, thaum lub cawv muaj peev xwm mus oxidation, esterification, thiab etherification. Lub compound yog hygroscopic thiab tuaj yeem nqus cov pa roj carbon dioxide los ntawm huab cua los tsim cov ntsev carbamate. Kev khaws cia rau hauv cov thawv kaw nruj nreem nyob rau hauv qhov chaw tsis zoo ntawm qhov kub thiab txias yog pom zoo. Kev sib cuag nrog cov neeg muaj zog oxidizing, acid chlorides, thiab isocyanates yuav tsum raug zam.

4 Amino 2 methylbutan 1 ol yog chiral amino cawv featuring ib ceg plaub carbon qaum nrog ib qho amine ntawm ib lub terminus thiab hydroxyl ntawm lwm qhov. Lub methyl ceg ntawm 2 txoj hauj lwm qhia txog qhov chaw stereogenic, ua rau cov khoom siv kho qhov muag thaum kho. Cov qauv qauv no sib txuas cov nucleophilicity ntawm thawj amine nrog hydrogen bonding peev xwm ntawm thawj cawv nyob rau hauv lub compact, hloov tau yooj yim. Ob pawg ua haujlwm tau tso cai rau chelation nrog cov hlau ions lossis kev koom tes hauv intramolecular hydrogen bonding, cuam tshuam rau ob qho tib si reactivity thiab conformation. Amino alcohols ntawm hom no muaj txiaj ntsig zoo hauv asymmetric synthesis li chiral auxiliaries, ligands, thiab tsev blocks rau cov tshuaj. Cov ceg ntoo alkyl muab cov lipophilicity nruab nrab, sib npaug dej solubility nrog daim nyias nyias permeability.

Chiral Tsev Thaiv hauv Asymmetric Synthesis
Cov amino cawv no ua haujlwm ntau yam pib cov khoom siv rau kev npaj chiral ligands thiab organocatalysts siv hauv kev hloov pauv enantioselective xws li hydrogenation, alkylation, thiab aldol cov tshuaj tiv thaiv. Thawj amine tuaj yeem hloov mus rau oxazolines, imines, lossis lwm pab pawg sib koom ua ke, thaum lub hydroxyl muab lub ntsiab lus rau kev khi hlau. Cov qauv branched tsim ib qho chaw zoo chiral ib puag ncig tseem ceeb rau kev ua tiav siab enantioselectivity hauv cov txheej txheem catalytic.

Pharmaceutical Intermediate
Hauv kev tshawb nrhiav tshuaj, 4 amino 2 methylbutan 1 ol yog ua haujlwm nyob rau hauv kev sib txuas ntawm cov tshuaj tiv thaiv kab mob hauv lub paj hlwb thiab cov kab mob metabolic. Cov amino cawv moiety tshwm nyob rau hauv ob peb bioactive molecules, nrog rau enzyme inhibitors thiab receptor modulators, qhov uas nws muaj peev xwm koom nyob rau hauv hydrogen bonding nrog active site residues. Lub chaw chiral tso cai rau kev npaj ntawm enantiomerically ntshiab cov neeg sib tw tshuaj nrog optimized pharmacological profiles.

Tsev Blocks rau Surfactants thiab Emulsifiers
Lub amphiphilic xwm ntawm cov compound no ua rau nws muaj txiaj ntsig rau kev npaj tsis yog ionic thiab cationic surfactants. Cov tshuaj tiv thaiv nrog fatty acids yields amides nrog cov khoom siv saum npoo av, thaum quaternization ntawm amine tsim cationic surfactants siv hauv cov ntaub softeners, cov plaub hau txias, thiab cov qauv tsim. Cov saw caj dab alkyl pab txhawb kev txhim kho emulsifying lub zog thiab kev ruaj ntseg hauv ntau hom kev tsim.

Ligand rau Hlau Complexes
Kev sib xyaw ua ke ntawm amine thiab cawv pub dawb ua rau qhov sib xyaw ua ke los ua ib qho kev sib tw ligand rau cov hlau hloov pauv, tsim cov chelate ruaj khov. Cov hlau complexes raug tshawb xyuas rau lawv cov kev ua haujlwm catalytic hauv oxidation thiab cross coupling tshua, nrog rau lawv lub peev xwm raws li MRI sib piv cov neeg ua haujlwm thiab cov qauv rau cov chaw ua haujlwm metalloenzyme. Cov ceg methyl tuaj yeem cuam tshuam rau stereochemistry thiab kev ruaj ntseg ntawm cov complexes.

Cim npe nrov: Tuam Tshoj 4-amino-2-methylbutan-1-ol, Tuam Tshoj 4-amino-2-methylbutan-1-ol manufacturers, lwm tus neeg